#1 "Go print me some skin, man."
Posted: Sun Oct 31, 2010 8:04 pm
I have not even imagined that this was possible until now - but the implications for this are enormous. I think of my experience working as helpdesk for a hospital network, and something like this would be a tremendous boon for emergency rooms alone, let alone (as the article mentioned) burn trauma units.Technology Review wrote:In a recent presentation at the American College of Surgeons Clinical Congress, researchers from the Wake Forest Institute for Regenerative Medicine showed off the results of a unique experiment involving a printer that uses living cells as its "ink."
The system, which lays down cells with the same fluid-based inkjet technology used in many printers, could print large swathes of living tissue directly onto the injuries of soldiers wounded on the battlefield. Covering burns and related wounds is of critical importance because, the scientists note, "any loss of full-thickness skin of more than 4 cm in diameter will not heal by itself."
Tests on mice revealed advanced healing by both the second and third week of recovery, with complete closure and formation of scar tissue by week three in treated (but not untreated) subjects. The printer has two heads, one of which ejects skin cells mixed with fibrinogen (a blood coagulant) and type I collagen (the main component of the connective tissue in scars). The other head ejects thrombin (another coagulant).
Like the components of quick-setting resins which must be kept separate until mixing causes a chemical reaction that hardens the resin, the products of the two print heads mix to immediately form fibrin, yet a third protein involved in the clotting of blood. The whole confection is topped by a layer of keratinocytes (i.e. skin cells), which are also printed.
Future iterations of the research will be conducted on pigs (which have skin that more closely resembles that of humans), and it's not clear when, if ever, such a device might appear in a field hospital in Afghanistan, not to mention your local burn center.
